Heredity of Retinal Vessel Tortuosity - Full Text View

Heredity of Retinal Vessel Tortuosity

This study has been completed.

Sponsors and Collaborators:	Glostrup University Hospital,Copenhagen Juvenile Diabetes Research Foundation
Information provided by:	Glostrup University Hospital,Copenhagen
ClinicalTrials.gov Identifier:	NCT00427063

Purpose

The purpose of this study is to asses the relative influence of genetic and environmental influence on the tortuosity of retinal arterioles in eyes of 218 healthy Danish twins aged 20-46 years. We expect to find a high heredity for the variation in tortuosity. This knowledge can contribute to the elucidation of the pathology in retinal diseases.

Condition

Retinopathy of Prematurity

MedlinePlus related topics:

Retinal Disorders

U.S. FDA Resources

Study Type:	Observational
Study Design:	Natural History, Cross-Sectional, Defined Population, Prospective Study

Official Title:	Heredity of Retinal Vessel Tortuosity - A Twin Study

Further study details as provided by Glostrup University Hospital,Copenhagen:

Estimated Enrollment:	218
Study Start Date:	January 1998
Estimated Study Completion Date:	December 1998

Detailed Description:

All persons underwent an ophthalmic examination including refraction, slit lamp biomicroscopy and digital fundus photography. Two independent graders (both with an MD degree) made a visual grading of the severity of tortuosity of the retinal arterioles in the fundus images.

Eligibility

Ages Eligible for Study:	20 Years to 46 Years
Genders Eligible for Study:	Both
Accepts Healthy Volunteers:	Yes

Criteria

Inclusion Criteria:

Samesex twin pairs of self-assessed good health

Exclusion Criteria:

Diabetes mellitus
Hypertension
Thyroid disease
Cataract or other opacities of the refractive media
Missing fundus photographs

Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00427063

Locations


Denmark, Copenhagen County
	Department of Ophthalmology Glostrup Hospital
	Glostrup, Copenhagen County, Denmark, DK-2600

Sponsors and Collaborators

Glostrup University Hospital,Copenhagen

Juvenile Diabetes Research Foundation

Investigators


Principal Investigator:	Michael Larsen, Prof. MD	Department of Ophthalmology Glostrup Hospital University of Copenhagen

More Information

Study ID Numbers:	Danish Twin Registry 1998
First Received:	January 25, 2007
Last Updated:	January 25, 2007
ClinicalTrials.gov Identifier:	NCT00427063
Health Authority:	Denmark: Ethics Committee

Keywords provided by Glostrup University Hospital,Copenhagen:

retinal vessels

tortuosity

Study placed in the following topic categories:

Eye Diseases

Retinopathy of prematurity

Infant, Newborn, Diseases

Infant, Premature, Diseases

Retinopathy of Prematurity

Retinal Diseases

ClinicalTrials.gov processed this record on September 23, 2008