Online Guide to Quitting

Preparing to Quit

MEDICATION GUIDE

NORTRIPTYLINE FACT SHEET

Description of Product:
Nortriptyline, also known as Aventyl, is generally prescribed to treat depression; however nortriptyline has been prescribed to assist with smoking cessation when the first line medications do not work. The use of nortriptyline for smoking cessation has not yet been approved by the FDA.
 
Dosing:
The first dose of nortriptyline is provided approximately 10-28 days before a quit attempt at a dose of 25 mg daily, increasing gradually to a target dose of 75-100 mg per day and continuing for 12 weeks.
 
Side Effects:
Side effects may include:
  • Drowsiness
  • Dry mouth
  • Lightheadedness
  • Blurred vision
  • Urinary retention
  • Tremor
 
Precautions:
This fact sheet was created to give you a general understanding of this medication. Please note that this fact sheet may not provide you with all the information you need to make the decision to use this product. Always read the instructions on the package carefully and talk with your doctor or pharmacist if you have questions. If you are pregnant, breastfeeding, or have a severe medical problem, talk with your doctor before starting any new medication.
 
Special Precautions:
Nortriptyline is not currently approved by the FDA for the treatment of nicotine addiction. Doctors sometimes prescribe these drugs to help people quit smoking when the first line of treatment does not help with cessation.

References: Information provided on the Medication Guide and Fact Sheets was obtained from a variety of sources, such as product information guides; manufacturers' Web sites, medical Web sites, and articles in the medical literature, including Corelli, R.L. & Hudman, K.S. (2006) Pharmacologic interventions for smoking cessation, Crit Care Nurs Clin N Am, 18, 39-51.


Smokefree.gov National Cancer Institute Centers for Disease Control and Prevention National Institutes of Health Department of Health and Human Services USA.gov