Online Guide to Quitting

Preparing to Quit

MEDICATION GUIDE

BUPROPION FACT SHEET

Description of Product:
Bupropion, also known as Zyban, helps to reduce nicotine withdrawal symptoms and the urge to smoke. Bupropion can be used safely with nicotine replacement products.
 
Dosing:
Take 150 mg every morning for 3 days. Then increase to 150 mg twice daily for 7 to 12 weeks. Unlike NRT products, smokers should begin treatment with bupropion 1 to 2 weeks before they quit smoking. For maintenance therapy, smokers can take 150 mg twice daily for up to 6 months.
 
Side Effects:
Side effects may include:
  • Dry mouth
  • Difficulty sleeping
  • Headaches
  • Dizziness
  • Skin rashes
 
Precautions:
This fact sheet was created to give you a general understanding of this medication. Please note that this fact sheet may not provide you with all the information you need to make the decision to use this product. Always read the instructions on the package carefully and talk with your doctor or pharmacist if you have questions. If you are pregnant, breastfeeding, or have a severe medical problem, talk with your doctor before starting any new medication.
 
Special Precautions:
Pregnancy/breastfeeding: Smokers who are pregnant or breastfeeding should try to quit first without assistance from Bupropion. Bupropion should be used during pregnancy only if the associated benefits outweigh the associated risks.

Seizures: Smokers who have a history of seizure, cranial trauma, or severe hepatic impairment must use bupropion with extreme caution.

References: Information provided on the Medication Guide and Fact Sheets was obtained from a variety of sources, such as product information guides; manufacturers’ Web sites, medical Web sites, and articles in the medical literature, including Corelli, R.L. & Hudman, K.S. (2006) Pharmacologic interventions for smoking cessation, Crit Care Nurs Clin N Am, 18, 39-51.


Smokefree.gov National Cancer Institute Centers for Disease Control and Prevention National Institutes of Health Department of Health and Human Services USA.gov