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Division of Intramural Research
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Research Investigators
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Online Research Resources Developed at NHGRI
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Division of Intramural Research Calendar
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Home Research Intramural Research
The Division of Intramural Research
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NHGRI's Division of Intramural Research plans and conducts a broad program of laboratory and clinical research to translate genomic and genetic research into a greater understanding of human genetic disease, and to develop better methods for the detection, prevention and treatment of heritable and genetic disorders. |
News and Events
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NHGRI's Dr. Benjamin Feldman and colleagues describe a method for viably isolating embryonic cells in zebrafish, which opens up numerous experimental possibilities for developmental biologists. The article, Transcriptional profiling of endogenous germ layer precursor cells identifies dusp4 as an essential gene in zebrafish endoderm specification, is in the August 26, 2008 issue of the Proceedings of the National Academy of Sciences.
[Full Text] 
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In an article in the August 26, 2008 issue of the Proceedings of the National Academy of Sciences, NHGRI's Dr. Kyungjae Myung and colleagues report on the role of the genes HLTF and SHPRH in maintaining genomic stability in human cells. Polyubiquitination of proliferating cell nuclear antigen by HLTF and SHPRH prevents genomic instability from stalled replication forks. [Full Text]
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| |  Elaine Ostrander, Ph.D., chief and senior investigator, Cancer Genetics Branch, NHGRI, has carved out a research niche with her study of dog genetics and human cancer. Dr. Ostrander is the subject of an inspiring profile in the August 2008 issue of The Scientist titled, Going to the Dogs.
[Full Text] The Scientist, August 2008
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| |  As deputy director of the National Institutes of Health Chemical Genomics Center (NCGC), James Inglese, Ph.D. and his colleagues use high-throughput screening to help other investigators identify small molecules that might make novel and effective tools for studying proteins, cellular functions, and biological processes involved in physiology or disease. Dr. Inglese is the subject of a researcher profile in the July 18, 2008 issue of ACS Chemical Biology titled, James Inglese: Uniting Biology and Chemistry in High Throughput.
[Full Text ] ACS Chemical Biology, July 18, 2008
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The 2008 NHGRI Intramural Research Brochure (60Mb)  |
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Current Topics in Genome Analysis 2008 |
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Division of Intramural Research News Features |
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News and Events Archive |
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NHGRI Event Webcasts |
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To view the PDFs on this page you will need Adobe Acrobat Reader.
Last Updated: September 3, 2008
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Genomics in Action
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K. J. Myung, Ph.D. won't just tell you about unstable genomes, he'll show you one. He studies genome instability, which is both a characteristic of and, in some cases, a trigger for many genetic diseases, including cancer. (more)
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