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Division of Intramural Research

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The Division of Intramural Research

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NHGRI's Division of Intramural Research plans and conducts a broad program of laboratory and clinical research to translate genomic and genetic research into a greater understanding of human genetic disease, and to develop better methods for the detection, prevention and treatment of heritable and genetic disorders.

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News and Events

bullet PNAS August 26, 2008 Cover NHGRI's Dr. Benjamin Feldman and colleagues describe a method for viably isolating embryonic cells in zebrafish, which opens up numerous experimental possibilities for developmental biologists. The article, Transcriptional profiling of endogenous germ layer precursor cells identifies dusp4 as an essential gene in zebrafish endoderm specification, is in the August 26, 2008 issue of the Proceedings of the National Academy of Sciences. [Full Text] New

bullet PNAS August 26, 2008 Cover In an article in the August 26, 2008 issue of the Proceedings of the National Academy of Sciences, NHGRI's Dr. Kyungjae Myung and colleagues report on the role of the genes HLTF and SHPRH in maintaining genomic stability in human cells. Polyubiquitination of proliferating cell nuclear antigen by HLTF and SHPRH prevents genomic instability from stalled replication forks. [Full Text] New

bullet Elaine Ostrander, Ph.D. Elaine Ostrander, Ph.D., chief and senior investigator, Cancer Genetics Branch, NHGRI, has carved out a research niche with her study of dog genetics and human cancer. Dr. Ostrander is the subject of an inspiring profile in the August 2008 issue of The Scientist titled, Going to the Dogs. [Full Text] The Scientist, August 2008

bullet James Inglese, Ph.D. As deputy director of the National Institutes of Health Chemical Genomics Center (NCGC), James Inglese, Ph.D. and his colleagues use high-throughput screening to help other investigators identify small molecules that might make novel and effective tools for studying proteins, cellular functions, and biological processes involved in physiology or disease. Dr. Inglese is the subject of a researcher profile in the July 18, 2008 issue of ACS Chemical Biology titled, James Inglese: Uniting Biology and Chemistry in High Throughput. [Full TextPDF file] ACS Chemical Biology, July 18, 2008

bullet The 2008 NHGRI Intramural Research Brochure (60Mb) PDF icon
bullet Current Topics in Genome Analysis 2008
bullet Division of Intramural Research News Features
bullet News and Events Archive
bullet NHGRI Event Webcasts

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Last Updated: September 3, 2008

Genomics in Action

K. J. Myung, Ph.D.
K. J. Myung, Ph.D. won't just tell you about unstable genomes, he'll show you one. He studies genome instability, which is both a characteristic of and, in some cases, a trigger for many genetic diseases, including cancer. (more)

See Also:

Division of Intramural Research News Features

Overview of the Division of Intramural Research

Genomics in Action Past Articles

Division of Intramural Research News and Events Archive

NHGRI Calendar

On Other Sites
Center for Inherited Disease Research (CIDR)

NIH Intramural Sequencing Center (NISC)

NIH Calendar of Events

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