Magnetic Resonance (MR) in Asthmatic Patients - Full Text View

Magnetic Resonance (MR) in Asthmatic Patients

This study has been suspended.
( no funding )

Sponsored by:	University Health Network, Toronto
Information provided by:	University Health Network, Toronto
ClinicalTrials.gov Identifier:	NCT00188487

Purpose

Asthma is a disease of small airways. Affected areas have reduced lung ventilation causing reflex vasoconstriction. MR perfusion imaging of the lungs is a sensitive method of imaging zonal lung perfusion.

Condition	Intervention	Phase
Asthma	Device: magnetic resonance imaging (MRI) of the thorax	Phase I

MedlinePlus related topics:

Asthma

U.S. FDA Resources

Study Type:	Interventional
Study Design:	Diagnostic, Non-Randomized, Open Label, Uncontrolled, Single Group Assignment, Efficacy Study

Official Title:	MR Perfusion Imaging in Asthmatic Patients

Further study details as provided by University Health Network, Toronto:

Primary Outcome Measures:

The correlation of MR lung perfusion analysis with computed tomography (CT) findings and pulmonary function tests

Estimated Enrollment:	80
Study Start Date:	September 2005
Estimated Study Completion Date:	December 2005

Detailed Description:

A cohort of 70 Asthmatic Patients and 10 controls, both sets of subjects have HRCT, MRI/A of the Thorax, and Pulmonary Function Tests to correlate the degree of pulmonary dysfunction with findings on imaging tests.

Eligibility

Ages Eligible for Study:	16 Years and older
Genders Eligible for Study:	Both
Accepts Healthy Volunteers:	Yes

Criteria

Inclusion Criteria:

All asthmatic patients are eligible.

Exclusion Criteria:

Patients in whom MRI is contraindicated

Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00188487

Locations


Canada, Ontario
	Toronto General Hospital
	Toronto, Ontario, Canada

Sponsors and Collaborators

University Health Network, Toronto

Investigators


Principal Investigator:	Narinder Paul, FRCP C	University Health Network, Toronto

More Information

Study ID Numbers:	05-0174
First Received:	September 12, 2005
Last Updated:	April 20, 2007
ClinicalTrials.gov Identifier:	NCT00188487
Health Authority:	Canada: Health Canada

Study placed in the following topic categories:

Asthma

ClinicalTrials.gov processed this record on September 22, 2008