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2005: HapMap Project Completed

The International HapMap Consortium published a catalog of human genetic variation that is expected to help speed the identification of genes associated with common diseases such as asthma, cancer, diabetes, and heart disease. While the Human Genome Project focused on the DNA sequence from a single individual, the HapMap project focused on variation in the genome and on human populations. The $138 million project was a three-year collaboration between more than 200 researchers from Canada, China, Japan, Nigeria and the United States. The new paper described the completion of a Phase I HapMap that contains more than 1 million markers of genetic variation. At the time of the publication, the consortium was nearing completion of a Phase II HapMap that would contain more than 3 million genetic markers.

More Information

References:

The International HapMap Consortium. Integrating ethics and science in the International HapMap Project. Nature Genetics, 5: 467-475. 2004. [Full Text]

International HapMap Consortium. A haplotype map of the human genome. Nature, 437: 1229-1320. 2005. [Full Text]

Klein, R.J., Zeiss, C., Chew, E.Y., Tsai, J.Y., et al. Complement factor H polymorphism in age-related macular degeneration. Science, 308: 385-389. 2005. [PubMed]

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Last Reviewed: April 17, 2008