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Myocardial Contrast Echocardiography in Congenital Heart Disease

This study is currently recruiting participants.
Verified by University Hospital Inselspital, Berne, December 2006

Sponsored by: University Hospital Inselspital, Berne
Information provided by: University Hospital Inselspital, Berne
ClinicalTrials.gov Identifier: NCT00412685
  Purpose

Patients with congenital heart disease in whom the right ventricle is exposed to pressure or volume overload show progressive systolic dysfunction of the right ventricle, the fact of which conveys substantial morbidity and mortality. The aim of this study is to investigate the myocardial perfusion in these patients by myocardial contrast echocardiography (MCE) in order to determine whether disturbed blood flow plays a role in the development of right ventricular systolic dysfunction.


Condition
D-Transposition of Great Arteries
Tetralogy of Fallot

MedlinePlus related topics:   Heart Diseases   

U.S. FDA Resources

Study Type:   Observational
Study Design:   Screening, Cross-Sectional, Defined Population, Prospective Study
Official Title:   Quantification of the Myocardial Microcirculation by Contrast Echocardiography In Adult Patients With Congenital Heart Disease

Further study details as provided by University Hospital Inselspital, Berne:

Estimated Enrollment:   45
Study Start Date:   August 2006
Estimated Study Completion Date:   August 2007

  Eligibility
Ages Eligible for Study:   18 Years to 80 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   Yes

Criteria

Inclusion Criteria:

  • D-TGA or Fallot-Tetralogy or Healthy person
  • written informed consent
  • Age >= 18 years

Exclusion Criteria:

  • Anaemia
  • Pregnancy and breast feeding
  • Diabetes mellitus
  • Contraindications to stress testing (ergometry or adenosine)
  • Known adverse reaction or hypersensitivity against V08DA (SonoVue) or its components or against adenosine
  Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00412685

Contacts
Contact: Tobias Rutz, MD     +41 6321 12 77     tobias.rutz@insel.ch    

Locations
Switzerland
University Hospital Inselspital     Recruiting
      Bern, Switzerland, 3010
      Sub-Investigator: Tobias Rutz, MD            

Sponsors and Collaborators
University Hospital Inselspital, Berne

Investigators
Principal Investigator:     Christian Seiler, Prof.     University Hospital Berne, Switzerland    
  More Information


Study ID Numbers:   70/06
First Received:   December 15, 2006
Last Updated:   December 15, 2006
ClinicalTrials.gov Identifier:   NCT00412685
Health Authority:   Switzerland: Swissmedic

Study placed in the following topic categories:
Transposition of great arteries
Heart Diseases
Cardiovascular Abnormalities
Transposition of Great Vessels
Great vessels transposition
Tetralogy of Fallot
Fallot tetralogy
Congenital Abnormalities
Heart Defects, Congenital

Additional relevant MeSH terms:
Cardiovascular Diseases

ClinicalTrials.gov processed this record on September 19, 2008




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