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Sponsors and Collaborators: |
University of Southern California Physical Therapy Clinical Research Network |
Information provided by: | University of Southern California |
ClinicalTrials.gov Identifier: | NCT00389012 |
The purpose of this study is to determine if treadmill training with body weight-support (BWST) is more effective at improving walking in individuals post-stroke than a resisted leg-cycling exercise program. In addition, we want to determine if training programs that combine leg strength training to treadmill walking provide an additional benefit to post-stroke walking outcomes.
Condition | Intervention | Phase |
Cerebrovascular Accident |
Procedure: exercise therapy Procedure: walking rehabilitation |
Phase II |
MedlinePlus related topics: | Exercise and Physical Fitness Rehabilitation |
Study Type: | Interventional |
Study Design: | Treatment, Randomized, Single Blind, Dose Comparison, Single Group Assignment, Efficacy Study |
Official Title: | Strength Training Effectiveness Post-Stroke (STEPS) |
Estimated Enrollment: | 80 |
Study Start Date: | May 2004 |
Estimated Study Completion Date: | January 2006 |
Impaired walking ability is a hallmark residual deficit that contributes to post-stroke walking disability . Impairment in lower extremity muscle strength is a significant contributor to decreased walking speed after stroke. No studies have combined task-specific locomotor training in combination with lower extremity strength training programs designed to improve post-stroke walking outcomes.
Participants will include individuals who are ambulatory, but walk slower than 1.0 m/sec and are at least 6 months post unilateral stroke.
Participants are stratified by initial comfortable walking speed (moderate >0.5 m/sec; severe <= 0.5 m/sec) and randomized to one of four exercise pairs: 1) body-weight supported treadmill training (BWST) and locomotor-based strength training (resistive cycling task, LBST), 2) BWST and LE muscle-specific strength training (MSST), 3) BWST and upper extremity ergometry (SHAM), and 4) LBST and SHAM. Training will occur 4 times per week for 6 weeks (24 total sessions). Exercise type in each exercise pair is alternated daily.
Primary outcomes include comfortable and fast overground walking speed, and distance walked in 6-minutes measured at baseline, after 12 and 24 treatment sessions and at a 6-month follow-up.
Ages Eligible for Study: | 18 Years and older |
Genders Eligible for Study: | Both |
Accepts Healthy Volunteers: | No |
Inclusion Criteria:
Exclusion Criteria:
United States, California | |||||
University of Southern California | |||||
Los Angeles, California, United States, 90089 | |||||
Rancho Los Amigos | |||||
Downey, California, United States, 90242 | |||||
United States, Illinois | |||||
Northwestern University | |||||
Chicago, Illinois, United States, 60611 |
University of Southern California |
Physical Therapy Clinical Research Network |
Principal Investigator: | Katherine J Sullivan, PhD, PT | Division of Biokinesiology and Physical Therapy, University of Southern California, Los Angeles, California |
Principal Investigator: | David A Brown, PhD, PT | Department of Physical Therapy and Movement Sciences, Feinberg School of Medicine, Northwestern University, Chicago, Illinois |
Principal Investigator: | Sara Mulroy, PhD, PT | Pathokinesiology Laboratory, Rancho Los Amigos National Rehabilitation Center, Downey, California |
Study ID Numbers: | 025024 |
First Received: | October 16, 2006 |
Last Updated: | October 16, 2006 |
ClinicalTrials.gov Identifier: | NCT00389012 |
Health Authority: | United States: Institutional Review Board |
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