|
|
|
|
|
Sponsored by: |
Liposome |
Information provided by: | NIH AIDS Clinical Trials Information Service |
ClinicalTrials.gov Identifier: | NCT00002019 |
To evaluate the safety, tolerance and efficacy of three different dosage regimens of Amphotericin B Lipid Complex (ABLC) compared to Fungizone (Amphotericin B) in patients with AIDS and cryptococcal meningitis.
Condition | Intervention |
Meningitis, Cryptococcal HIV Infections |
Drug: Amphotericin B, Lipid-based Drug: Amphotericin B |
MedlinePlus related topics: | AIDS Meningitis |
ChemIDplus related topics: | Amphotericin B Lipids |
Study Type: | Interventional |
Study Design: | Treatment, Dose Comparison, Safety Study |
Official Title: | Safety and Efficacy of Amphotericin B Lipid Complex in the Treatment of Cryptococcal Meningitis in Patients With the Acquired Immunodeficiency Syndrome |
Ages Eligible for Study: | 18 Years and older |
Genders Eligible for Study: | Both |
Accepts Healthy Volunteers: | No |
Inclusion Criteria
Concurrent Medication:
Allowed:
Patients must have the following:
Exclusion Criteria
Co-existing Condition:
Patients with the following conditions or symptoms are excluded:
Concurrent Medication:
Excluded:
Patients with the following are excluded:
Prior Medication:
Excluded within 4 weeks of study entry:
United States, California | |||||
Harbor - UCLA Med Ctr | |||||
Torrance, California, United States, 90502 | |||||
United States, Connecticut | |||||
Dr Thomas Patterson | |||||
New Haven, Connecticut, United States, 06510 | |||||
United States, District of Columbia | |||||
Walter Reed Army Med Ctr | |||||
Washington, District of Columbia, United States, 203075001 | |||||
United States, Illinois | |||||
Rush Presbyterian - Saint Luke's Med Ctr | |||||
Chicago, Illinois, United States, 60612 | |||||
United States, Maryland | |||||
Natl Naval Med Ctr | |||||
Bethesda, Maryland, United States, 20889 | |||||
United States, Massachusetts | |||||
Univ Hosp | |||||
Boston, Massachusetts, United States, 02118 | |||||
United States, New Jersey | |||||
East Orange Veterans Administration Med Ctr | |||||
East Orange, New Jersey, United States, 07018 | |||||
Saint Michael's Med Ctr | |||||
Newark, New Jersey, United States, 07102 | |||||
United States, New York | |||||
Mount Sinai Med Ctr / Jack Martin Fund Clinic | |||||
New York, New York, United States, 10029 | |||||
Saint Luke's - Roosevelt Hosp Ctr | |||||
New York, New York, United States, 10025 | |||||
Dr Dorothy Friedberg | |||||
New York, New York, United States, 10016 | |||||
New York Univ Med Ctr | |||||
New York, New York, United States, 10016 | |||||
Cornell Univ Med College | |||||
New York, New York, United States, 10021 | |||||
Beth Israel Med Ctr / Peter Krueger Clinic | |||||
New York, New York, United States, 10003 | |||||
Mount Sinai Med Ctr | |||||
New York, New York, United States, 10029 | |||||
United States, Pennsylvania | |||||
Buckley Braffman Stern Med Associates | |||||
Philadelphia, Pennsylvania, United States, 19107 | |||||
United States, Texas | |||||
Univ TX Galveston Med Branch | |||||
Galveston, Texas, United States, 77550 | |||||
Audie L Murphy Veterans Administration Hosp | |||||
San Antonio, Texas, United States, 78284 | |||||
United States, Utah | |||||
Univ of Utah School of Medicine | |||||
Salt Lake City, Utah, United States, 84132 |
Liposome |
al-Haddadin D, Fan-Havard P, Boghossian J, Marton R, Vincent-Graber D, Dungo L, Eng RH, Johnson ES. Amphotericin B-lipid complex (ABLC) in treatment of cryptococcal meningitis in AIDS. Int Conf AIDS. 1992 Jul 19-24;8(2):B109 (abstract no PoB 3132)
  |
Study ID Numbers: | 051A |
First Received: | November 2, 1999 |
Last Updated: | June 23, 2005 |
ClinicalTrials.gov Identifier: | NCT00002019 |
Health Authority: | United States: Food and Drug Administration |
|
|
|
|
|
|