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Editor-in-Chief Melissa Norton, MD
Biology Editor Penelope Webb, PhD
In-house Editor Danielle Talbot
Welcome to BMC Structural Biology published by BioMed Central
BMC Structural Biology is an open access journal publishing original peer-reviewed research articles in investigations into the structure and function of biological macromolecules.
BMC Structural Biology (ISSN 1472-6807) is indexed/tracked/covered by PubMed, MEDLINE, BIOSIS, CAS, Scopus, EMBASE, Thomson Reuters (ISI) and Google Scholar.
Featured articles
BMC Structural Biology 2008, 8 :29
The addition of the solvent 2,4-methyl-2-pentanediol (MPD) protects lysozyme from the denaturing agent SDS and even allows the formation of crystals with a very similar protein structure to the native protein.
BMC Structural Biology 2008, 8 :21
The Protein Structure and Interaction Analyzer accurately and easily predicts protein interaction sites within large numbers of structures and complexes, by using a new distance algorithm and integrating established protein interaction algorithms.
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Research article
Docking of molecules identified in bioactive medicinal plants extracts into the p50 NF-kappaB transcription factor: correlation with inhibition of NF-kappaB/DNA interactions and inhibitory effects on IL-8 gene expression Laura Piccagli, Enrica Fabbri, Monica Borgatti, Valentino Bezzerri, Irene Mancini, Elena Nicolis, Maria C Dechecchi, Ilaria Lampronti, Giulio Cabrini, Roberto Gambari BMC Structural Biology 2008, 8 :38 (3 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research article
Protein-segment universe exhibiting transitions at intermediate segment length in conformational subspaces Kazuyoshi Ikeda, Takatsugu Hirokawa, Junichi Higo, Kentaro Tomii BMC Structural Biology 2008, 8 :37 (13 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Contact prediction in protein modeling: Scoring, folding and refinement of coarse-grained models Dorota Latek, Andrzej Kolinski BMC Structural Biology 2008, 8 :36 (11 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Statistical analysis of the Bacterial Carbohydrate Structure Data Base (BCSDB): Characteristics and diversity of bacterial carbohydrates in comparison with mammalian glycans Stephan Herget, Philip V Toukach, Rene Ranzinger, William E Hull, Yuriy A Knirel, Claus-Wilhelm von der Lieth BMC Structural Biology 2008, 8 :35 (11 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research article
Alternating evolutionary pressure in a genetic algorithm facilitates protein model selection Marc N Offman, Alexander L Tournier, Paul A Bates BMC Structural Biology 2008, 8 :34 (1 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Structural characterization of CA1462, the Candida albicans thiamine pyrophosphokinase S BMC Structural Biology 2008, 8 :33 (24 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Structural analysis of urate oxidase in complex with its natural substrate inhibited by cyanide: Mechanistic implications Laure Gabison, Thierry Prang BMC Structural Biology 2008, 8 :32 (20 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Systematic analysis of the effect of multiple templates on the accuracy of comparative models of protein structure Suvobrata Chakravarty, Sucheta Godbole, Bing Zhang, Seth Berger, Roberto Sanchez BMC Structural Biology 2008, 8 :31 (16 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Software
Graphical analysis of NMR structural quality and interactive contact map of NOE assignments in ARIA Benjamin Bardiaux, Aymeric Bernard, Wolfgang Rieping, Michael Habeck, Th BMC Structural Biology 2008, 8 :30 (5 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Protecting role of cosolvents in protein denaturation by SDS: a structural study Catherine Michaux, Jenny Pouyez, Johan Wouters, Gilbert G Priv BMC Structural Biology 2008, 8 :29 (3 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research
Three dimensional structure directs T-cell epitope dominance associated with allergy Scott J Melton, Samuel J Landry Clinical and Molecular Allergy 2008, 6 :9 (15 [Abstract ] [Provisional PDF ]
Research article
TOPS++FATCAT: fast flexible structural alignment using constraints derived from TOPS+ Strings Model Mallika Veeramalai, Yuzhen Ye, Adam Godzik BMC Bioinformatics 2008, 9 :358 (31 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research article
Impact of residue accessible surface area on the prediction of protein secondary structures Amir Momen-Roknabadi, Mehdi Sadeghi, Hamid Pezeshk, Sayed-Amir Marashi BMC Bioinformatics 2008, 9 :357 (31 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Methodology article
Alignment of protein structures in the presence of domain motions Roberto Mosca, Barbara Brannetti, Thomas R Schneider BMC Bioinformatics 2008, 9 :352 (27 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Methodology article
Protein structure search and local structure characterization Shih-Yen Ku, Yuh-Jyh Hu BMC Bioinformatics 2008, 9 :349 (22 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Methodology article
An enhanced partial order curve comparison algorithm and its application to analyzing protein folding trajectories Hong Sun, Hakan Ferhatosmanoglu, Motonori Ota, Yusu Wang BMC Bioinformatics 2008, 9 :344 (18 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Software
MotifCluster: an interactive online tool for clustering and visualizing sequences using shared motifs Micah Hamady, Jeremy Widmann, Shelley D Copley, Rob Knight Genome Biology 2008, 9 :R128 (15 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Database
RNA STRAND: The RNA Secondary Structure and Statistical Analysis Database Mirela Andronescu, Vera Bereg, Holger H Hoos, Anne Condon BMC Bioinformatics 2008, 9 :340 (13 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Myosin-Vb functions as a dynamic tether for peripheral endocytic compartments during transferrin trafficking D William Provance Jr, Erin J Addison, Patrick R Wood, David Z Chen, Colleen M Silan, John A Mercer BMC Cell Biology 2008, 9 :44 (7 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research
The hyperbolic effect of density and strength of inter beta-cell coupling on islet bursting: a theoretical investigation Aparna Nittala, Xujing Wang Theoretical Biology and Medical Modelling 2008, 5 :17 (3 [Abstract ] [Full Text ] [PDF ] [PubMed ] [Related articles ]
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