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C06 | Research Facilities Construction Grants
To provide matching Federal funds, up to 75 percent, for construction or major remodeling to create new research facilities. In addition to basic research laboratories, this may include, under certain circumstances, animal facilities and/or limited clinical facilities where they are an integral part of an overall research effort.
NIH Policy
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| F31 | Predoctoral Individual National Research Service Award (NRSA)
To provide predoctoral individuals with supervised research training in specified health and health-related areas leading toward the research degree (e.g., Ph.D.).
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| F31 | Predoctoral Fellowship--Minority Students
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| F31 | Predoctoral Fellowship--Students with Disabilities
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| F32 | National Research Service Award for Individual Postdoctoral Fellows
To provide postdoctoral research training to individuals to broaden their scientific background and extend their potential for research in specified health-related areas.
Program Announcements
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| F33 | NIH National Research Service Awards for Senior Fellows
To provide opportunities for experienced scientists to make major changes in the direction of research careers, to broaden scientific background, to acquire new research capabilities, to enlarge command of an allied research field, or to take time from regular professional responsibilities for the purpose of increasing capabilities to engage in health-related research.
Program Announcements
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| K01 | The Howard Temin Award; Guidelines
Has been replaced by K99/R00
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| K01 | Research Scientist Development Award - Research & Training
For support of a scientist, committed to research, in need of both advanced research training and additional experience.
Program Announcements
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| K05 | Established Investigator Award in Cancer Prevention, Control, Behavioral, and Population Research
For the support of a research scientist qualified to pursue independent research which would extend the research program of the sponsoring institution, or to direct an essential part of this research program.
Program Announcements
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| K07 | Cancer Prevention, Control, Behavioral, and Population Sciences Career Development Award
Program Announcements
NCI Guidelines
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| K08 | Clinical Investigator Award (CIA)
To provide the opportunity for promising medical scientists with demonstrated aptitude to develop into independent investigators, or for faculty members to pursue research aspects of categorical areas applicable to the awarding unit, and aid in filling the academic faculty gap in these shortage areas within health profession's institutions of the country.
Program Announcements
NCI Guidelines
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| K08 | Minorities in Clinical Oncology
Program Announcements
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| K12 | Institutional Clinical Oncology Research Career Development Award
To support a newly trained clinician appointed by an institution for development of independent research skills and experience in a fundamental science within the framework of an interdisciplinary research and development program.
Program Announcements
NCI Guidelines
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| K22 | The NCI Transition Career Development Award for Underrepresented Minorities
To provide support to outstanding newly trained basic or clinical investigators to develop their independent research skills through a two phase program; an initial period involving and intramural appointment at the NIH and a final period of support at an extramural institution. The award is intended to facilitate the establishment of a record of independent research by the investigator in order to sustain or promote a successful research career.
Program Announcements
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| K22 | The NCI Scholars Program
To provide an opportunity for outstanding new investigators to begin their independent research careers, first within the special environment of the National Cancer Institute and then at an institution of their choice. Specifically, this Program provides necessary resources to initiate an independent research program of 3 to 4 years at the NCI followed by an extramural funding mechanism (K22) to support their research program for 2 years at the extramural institution to which they are recruited.
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| K23 | Mentored Patient-Oriented Research Career Development Award
Program Announcements
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| K23 | Mentored Patient-Oriented Research Career Development Award for Underrepresented Minorities
To provide support for the career development of investigators who have made a commitment of focus their research endeavors on patient-oriented research. This mechanism provides support for a 3 year minimum up to 5 year period of supervised study and research for clinically trained professionals who have the potential to develop into productive, clinical investigators.
Program Announcements
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| K24 | Midcareer Investigator Award in Patient-Oriented Research
To provide support for clinicians to allow them protected time to devote to patient-oriented research and to act as mentors for beginning clinical investigators. The target candidates are outstanding clinical scientists engaged in patient-oriented research who are within 15 years of their specialty training, who can demonstrate the need for a period of intensive research focus as a means of enhancing their clinical research careers, and who are committed to mentoring the next generation of clinical investigators in patient-oriented research.
Program Announcements
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| K25 | Mentored Quantitative Research Career Development Award
To support the career development of investigators with non-biomedical quantitative and engineering backgrounds who have made a commitment to focus their research career on basic or clinical medical research.
Program Announcements |
| K99/R00 | Howard Temin Pathway to Independence Award
The NIH Pathway to Independence Award provides an opportunity for promising postdoctoral scientists to receive both mentored and independent research support from the same award. The initial phase will provide 1-2 years of mentored support for highly promising, postdoctoral research scientists followed by up to 3 years of independent support contingent on securing an independent research position.
Program Announcements
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| L30 | Loan Repayment Program for Clinical Researchers
To provide for the repayment of the educational loan debt of qualified health professionals involved in clinical research. Qualified health professionals who contractually agree to conduct qualified clinical research are eligible to apply for this program.
NIH Guidelines
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| L32 | Loan Repayment Program for Clinical Researchers from Disadvantaged Backgrounds
To provide for the repayment of the educational loan debt of qualified health professionals from disadvantaged backgrounds involved in clinical research. Qualified health professionals from disadvantaged backgrounds who contractually agree to conduct qualified clinical research are eligible to apply for this program.
NIH Guidelines
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| L40 | Loan Repayment Program for Pediatric Research
To provide for the repayment of the educational loan debt of qualified health professionals involved in research directly related to diseases, disorders, and other conditions in children. Qualified health professionals who contractually agree to conduct qualified pediatric research are eligible to apply for this program.
NIH Guidelines
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| L50 | Loan Repayment Program for Contraception and Infertility Research
To provide for the repayment of the educational loan debt of qualified health professionals (including graduate students) who contractually agree to commit to conduct qualified contraception and/or infertility research.
NIH Guidelines
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| L60 | Loan Repayment Program for Health Disparities Research (HD-LRP)
To provide for the repayment of the educational loan debt of qualified health professionals involved in minority health and health disparities research, for the purposes of improving minority health and reducing health disparities. Qualified health professionals who contractually agree to conduct qualified minority health disparities research or other health disparities research eligible to apply for this program.
NIH Guidelines
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| P01 | Research Program Projects
To support multidisciplinary or multifaceted research programs that have a focused theme. Each component project should be directly related to and contribute to the common theme.
Program Announcements
P01 Guidelines
Supplemental Material
Review Guide |
| P20/P30 | Information for Centers and Scientists Administrative & General Information
Cancer Centers Programs
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| P20 | Exploratory Grants
To support planning for new programs, expansion or modification of existing resources, and feasibility studies to explore various approaches to the development of interdisciplinary programs that offer potential solutions to problems of special significance to the mission of the NIH. These exploratory studies may lead to specialized or comprehensive centers.
Program Announcements
NCI Guidelines
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| P30 | Center Core Grants
To support shared use of resources and facilities for categorical research by investigators from different disciplines who provide a multidisciplinary approach to a joint research effort, or by investigators from the same discipline who focus on a common research problem. The core grant is integrated with the center's component projects or Program Projects, though funded independently from them. This support, by providing more accessible resources, is expected to assure greater productivity than that provided through the separate projects and Program Projects.
Program Announcements
Cancer Centers Program
Scientific Information for Centers and Researchers
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| P41 | Biotechnology Resource Grant Program |
| P50 | Specialized Center Grants
To support any part of the full range of research and development from very basic to clinical; may involve ancillary supportive activities such as protracted patient care necessary to the primary research or R & D effort. The spectrum of activities comprise a multidisciplinary attack on a specific disease entity or biomedical problem area. There grants differ from program project grants in that they are usually developed in response to an announcement of the programmatic needs to an Institute or Division and subsequently receive continuous attention from staff. Centers may also serve as regional or national resources for special research purposes.
Program Announcements
SPORE Guidelines; July 2006
Specialized Programs of Research Excellence (SPORE) Website
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| R01 | Modular Research Grant Application
The modular research grant procedures will affect the NIH peer review process by enabling reviewers to evaluate proposed project budgets on the basis of a general, expert estimate of the total effort and resources required to conduct the proposed research. Reviewers will recommend changes in a proposed project's budget in $25,000 modules. NIH Institute staff will continue to make all final award decisions.
NIH Modular Research Grant Applications
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| R01 | Research Project
Grants are awarded to institutions to allow a Principal Investigator to pursue a scientific focus or objective in his or her area of interest and competence. Institutional sponsorship assures the NIH that the institution will provide facilities necessary to conduct the research and will be accountable for the grant funds. Applications are accepted for health-related research and development in all areas within the scope of the NIH's mission.
Program Announcements
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| R03 | Small Research Grants
Small grants provide research support, specifically limited in time and amount, for activities such as pilot projects, testing of new techniques, or feasibility studies of innovative, high-risk research, which would provide a basis for more extended research.
Program Announcements
NIH Guidelines
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| R13 | Conference
The NIH provides funding for conferences to coordinate, exchange, and disseminate information related to its program interests. Generally, such awards are limited to participation with other organizations in supporting conferences rather than provision of sole support. Costs eligible for support include salaries, consultant services, equipment rental, travel, supplies, conference services, and publications. Prospective applicants are encouraged to inquire in advance concerning possible interest on the part of an awarding Institute/Center (IC), and to obtain more information on application procedures and costs.
NIH Guidelines
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| R15 | The NIH Academic Research Enhancement Awards (AREA)
To enhance the research environment of educational institutions that have not been traditional recipients of NIH research funds, this award provides limited funds to those institutions' faculty members to develop new research projects or expand ongoing research activities in health sciences and to encourage students to participate in the research activity. As funds are anticipated to continue to be available each year, the NIH is now inviting applications for AREA grants through a standing, ongoing Program Announcement.
NIH Guidelines
Program Announcements
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| R18 | Research Demonstration and Dissemination Projects
To provide support designed to develop, test, and evaluate health service activities, and to foster the application of existing knowledge for the control of categorical diseases.
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| R21 | Exploratory/Developmental Grants
To encourage the development of new research activities in categorical program areas. (Support generally is restricted in level of support and duration.)
Program Announcements
NIH Guidelines
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| R24 | Resource-Related Research Projects
To support research projects that will enhance the capability of resources to serve biomedical research.
Program Announcements
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| R25 | Cancer Education Projects
Program Announcements
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| R25T | Cancer Education and Career Development Program
To support development and/or implementation of a program related to a category in one or more of the areas of education, information, training, technical assistance, coordination, or evaluation.
Program Announcements
NCI Guidelines
Supplements to R25T Guidelines: Nov 2001; PDF Format
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| R29 | First Independent Research Support and Transition (FIRST) Award
Has been discontinued across NIH.
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| R33 | Exploratory/Developmental Grants Phase II
To provide a second phase for support of innovative exploratory and developmental research activities initiated under the R21 mechanism. Although only R21 awardees are generally eligible to apply for R33 support, specific program initiatives may establish eligibility criteria under which applications could be accepted from applicants who demonstrate program competency equivalent to that expected under R33.
Program Announcements
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| R34 | Clinical Trial Planning Grant
To provide support for the initial development of a clinical trial, including the establishment of the research team; the development of tools for data management and oversight of the research; and, the development of a trial design and other essential elements of the study, such as the protocol, recruitment strategies, and procedure manuals.
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| R36 | Dissertation Award
To support dissertation research costs of students in accredited research doctoral programs in the United States (including Puerto Rico and other U.S. territories or possessions). Dissertation awards are not renewable.
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| R37 | Method to Extend Research in Time (MERIT) Award
To provide long-term grant support to investigators whose research competence and productivity are distinctly superior and who are highly likely to continue to perform in an outstanding manner. Investigators may not apply for a MERIT award. Program staff and/or members of the cognizant National Advisory Council/Board will identify candidates for the MERIT award during the course of review of competing research grant applications prepared and submitted in accordance with regular PHS requirements.
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Small Business Innovation Research (SBIR) and Small Business Technology Transfer (STTR) Programs
The NIH welcomes grant applications from small businesses in any biomedical or behavioral research area as described in the solicitations below. Support under the SBIR program is normally provided for 6 months/$100,000 for Phase I, and 2 years/$500,000 for Phase II. However, applicants may propose longer periods of time and greater amounts of funds necessary for completion of the project. |
| R41 | Small Business Technology Transfer (STTR) Grants - Phase I
To support cooperative R&D projects between small business concerns and research institutions, limited in time and amount, to establish the technical merit and feasibility of ideas that have potential for commercialization.
Program Announcements NCI Resource Center
Advice and Information on SBIR/STTR Programs
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| R42 | Small Business Technology Transfer (STTR) Grants - Phase II
To support in-depth development of cooperative R&D projects between small business concerns and research institutions, limited in time and amount, whose feasibility has been established in Phase I and that have potential for commercial product(s) or service(s).
Program Announcements
NCI Resource Center
Advice and Information on SBIR/STTR Programs
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| R43 | Small Business Innovation Research Grants (SBIR) - Phase I
To support projects, limited in time and amount, to establish the technical merit and feasibility of R&D ideas that may ultimately lead to commercial products or services.
Program Announcements
NCI Resource Center
Advice and Information on SBIR/STTR Programs
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| R44 | Small Business Innovation Research Grants (SBIR) - Phase II
To support in-depth development of R&D ideas whose feasibility have been established in Phase I that are likely to result in commercial products or services.
Program Announcements
NCI Resource Center
Advice and Information on SBIR/STTR Programs
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| R55 | James A. Shannon Director's Award
To provide a limited award to investigators to further develop, test, and refine research techniques; perform secondary analysis of available data sets; test the feasibility of innovative and creative approaches; and conduct other discrete projects that can demonstrate their research capabilities and lend additional weight to their already meritorious applications.
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| S06 | Minority Biomedical Research Support (MBRS)
To strengthen the biomedical research and research training capability of ethnic minority institutions, and thus establish a more favorable milieu for increasing the involvement of minority faculty and students in biomedical research.
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| S15 | Small Instrumentation Grants Program |
| TU2 |
Institutional National Research Service Award with Involvement of NIH Intramural Faculty
The cooperative agreement counterpart to the T32, this award enables institutions to provide research-training experiences for graduate students and postdoctoral scientists in specified shortage areas. In addition, these awards involve identified NIH Intramural Staff who serve as a part of the training faculty and participate in the operation of the training program. |
| T15 | Continuing Education Training Program
Program Announcements
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| T32 | NIH National Research Service Award - Institutional Research Training Grants
To enable institutions to make National Research Service Awards to individuals selected by them for predoctoral and postdoctoral research training in specified shortage areas.
Program Announcements
NCI Supplemental Policy
Supplemental Guideline |
| T34 |
MARC Undergraduate NRSA Institutional Grants
To enable minority institutions to make National Research Service Awards to individuals selected by them for predoctoral and postdoctoral research training in the biomedical and behavioral sciences.
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| U01 |
Research Project
To support a discrete, specified, circumscribed project to be performed by the named investigator(s) in an area representing his specific interest and competencies.
Program Announcements
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| U10 |
Cooperative Clinical Research--Cooperative Agreements
To support clinical evaluation of various methods of therapy and/or prevention in specific disease areas. These represent cooperative programs between sponsoring institutions and participating principal investigators, and are usually conducted under established protocols.
Program Announcements |
| U13 | Conference--Cooperative Agreements
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| U19 |
Research Program--Cooperative Agreements
To support a research program of multiple projects directed toward a specific major objective, basic theme or program goal, requiring a broadly based, multidisciplinary and often long-term approach. |
| U24 |
Resource-Related Research Projects--Cooperative Agreements
To support research projects contributing to improvement of the capability of resources to serve biomedical research. |
| U42 |
Animal (Mammalian and Nonmammalian) Model, and Animal and Biological Materials (NCRR)
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| U43 |
Small Business Innovative Research Grant (SBIR/Phase I)
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| U44 |
Small Business Innovative Research Grant (SBIR/Phase II)
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| U54 |
Specialized Center-Cooperative Agreements
To support any part of the full range of research and development from very basic to clinical; may involve ancillary supportive activities such as protracted patient care necessary to the primary research or R&D effort. The spectrum of activities comprises a multidisciplinary attack on a specific disease entity or biomedical problem area. These differ from program project in that they are usually developed in response to an announcement of the programmatic needs of an Institute or Division and subsequently receive continuous attention from its staff. Centers may also serve as regional or national resources for special research purposes, with funding component staff helping to identify appropriate priority needs.
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| U56 |
Exploratory Grants--Cooperative Agreements
To support planning for new programs, expansion or modification of existing resources, and feasibility studies to explore various approaches to the development of interdisciplinary programs that offer potential solutions to problems of special significance to the mission of the NIH. These exploratory studies may lead to specialized or comprehensive centers. Substantial Federal programmatic staff involvement is intended to assist investigators during performance of the research activities, as defined in the terms and conditions of award.
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