=> DATA FILE SET-LEVEL: FRC94A02
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Description:
This analytic data file set consists of three files generated for a retrospective cohort mortality study by Donna Cragle of white males employed during 1951-1989 at the Feed Materials Production Center (FMPC) in Fernald Ohio.
This study of white males employed between 1951 and 1989 had a total of 121,000 person-years of follow-up. Results for the combined cohort showed statistically significantly elevated standardized mortality ratios (SMRS) for all cancers combined (1.15) and prostate cancer (1.58). Investigating SMRs separately for salaried and nonsalaried workers, there were notable differences between the mortality patterns of the two groups. Salaried workers had a statistically significantly increased SMR only for stomach cancer (2.61), as contrasted with all cancers combined (1.21), lung cancer (1.26), and motor vehicle accidents (1.59) for nonsalaried workers. No deaths from bone sarcomas were found in either group. The healthy worker effect was evident in the statistically significant all-causes SMR of 0.71 for salaried workers. The corresponding SMR for nonsalaried workers was 0.95 with an upper confidence bound of 1.01. Dose-response relationships were found only for cumulative external dose and lung cancer and for cumulative internal dose and nonmalignant respiratory diseases.
The demographic and work history analytic file (DLC4014) contains a record, which includes vital status as of January 1, 1990, for each of the 4,014 members of the cohort. There are two exposure files. NLOEXTL contains annual deep doses in cGy (rads) from external radiation sources, while NLOINTL contains annual calculated lung doses in cGy from internal radiation sources.
The last Social Security Administration (SSA) submission for this population provided "alive" status as of January 1, 1985; the "alive" category is no longer obtainable from SSA.
However, the National Death Index (NDI) provides a record of all deaths occurring since January 1, 1979. If not identified as deceased by SSA or NDI, individuals last known to be alive before January 1, 1979 were considered lost to follow-up on the last date known alive. Those classified as unknown after January 1, 1979 were considered alive at the end of the study. There were 1,064 deaths from all causes with death certificates available for 99.0% of these individuals.
There are two exposure files. NLOEXTL contains annual deep doses in cGy (rads) from external radiation sources, and NLOINTL contains annual calculated lung doses in cGy from internal radiation sources.
The FMPC was involved in processing uranium ore concentrate and uranium of low grade enrichment into fabricated uranium metal products and in the production of thorium metal. Operations began in late 1951 with 85% of the cohort being hired before 1960. Employment at the facility reached its peak in 1956 and slowly decreased until operations halted in July of 1989. In addition to radiation and thorium, potential exposures included kerosene, tributyl phosphate, and other solvents.
Number of data files: 3
Cohort Size: 4014
Races: White
Sexes: male
Diseases: ALL
Earliest Exposure: 01/01/1951
Latest Exposure: 12/31/1989
Follow-Up: 01/01/1990
Exposure Type: radiation, chemical
Exposure Agent: uranium and thorium, potential exposures included kerosene, tributyl phosphate, and other solvents
Sites: Fernald
Contact Information:
Cragle, Dr. Donna
(423) 576-2866
Fax: 423 576-9557
Email: cragled@orau.gov