Post-Traumatic Stress Disorder (Adult) Research Study
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Adult Posttraumatic Stress Disorder (PTSD) Investigational New Medicine Treatment Trial: Evaluation of the Efficacy of the NK1 Antagonist GR205171 in Posttraumatic Stress Disorder
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Adult Posttraumatic Stress Disorder (PTSD) Investigational New Medicine Treatment Trial: Evaluation of the Efficacy of the NK1 Antagonist GR205171 in Posttraumatic Stress Disorder
Have you experienced a traumatic event? Since the trauma, have you developed symptoms such as nightmares, flashbacks, anxiety, avoidance of people or places that remind you of the trauma, sleep disturbances or difficulty concentrating? If you suffer from these symptoms you may have Posttraumatic Stress Disorder (PTSD). You may be eligible to participate in a treatment trial of an investigational new drug, an NK1 antagonist. Participants must be 18 to 65 and able to come to the NIH Clinical Center in Bethesda for a total of 12 weekly visits. NK1 antagonists may play a role in the symptoms of PTSD through their influence on a substance in the brain called Substance P.
To find out if you qualify or for more information, please call 1-866-505-1033 or email us at ptsdstudies@mail.nih.gov.
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Disease and Treatment Information |
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Post-Traumatic Stress Disorder (Adult) Research Study
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Human Resilience & Posttraumatic Stress Disorder (PTSD)
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Are you an adult trauma survivor? You may be eligible to participate in a study of brain changes and psychological characteristics of people who are resilient to trauma. It will examine and compare responses in three categories of subjects: 1) women who have been exposed to a significant traumatic event and suffer symptoms of post-traumatic stress disorder (PTSD) severe enough to interfere with their ability to function; 2) women who have been exposed to a significant traumatic event and do not suffer PTSD symptoms severe enough to interfere with their ability to function; and 3) women who have never been exposed to a significant traumatic event. Most people who are exposed to trauma recover well from the adversity. Some gain greater self-confidence of strengthening personal relationships. Others, however, develop PTSD and may have repeated thoughts, images, and dreams of the trauma; feel upset when reminded of the traumatic event; avoid places or people that remind them of the trauma; feel detached from others; have difficulty sleeping and concentrating; or startle easily. Understanding these differences may help lead to improved treatments.
To find out if you qualify or for more information, please call 1-866-627-6464 or email us at giesenh@mail.nih.gov.
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Protocol Information |
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