Public Health
NICEATM-ICCVAM Home >> Test Method Evaluations>> Acute Oral Toxicity >> Up-and-Down Procedure

Up-and-Down Procedure for Acute Oral Toxicity
Site Map
Site Map
Overview and
Recommendations		 Peer Review
Evaluation Report		 Presentations and References

Peer Review Evaluation Report

An Independent Scientific Peer Review meeting was held on July 25, 2000, at the Sheraton-Crystal City, in Arlington, VA, to evaluate the usefulness and validation status of the revised UDP. NICEATM assembled available data on the revised UDP into a Background Review Document (BRD), which was used by the Peer Review Panel to assess the method. A UDP Peer Review Panel Teleconference meeting was held on August 21, 2001, at NIEHS, RTP, NC.

Up-and-Down Procedure Report

(NIH Publication No. 02-4501 - November 2001)

Volume 1 [PDF - 1.5 MB] and
Volume 2 [PDF - 2.2 MB]

View Table of Contents in HTML format

UDP Report Cover

ICCVAM Evaluation

  • Agenda [PDF]

  • Minutes of the public Independent Peer Review Panel meeting, on July 25, 2000, Sheraton Imperial-Crystal City in Arlington, VA [PDF]

  • Minutes of the UDP Peer Review Panel Teleconference Meeting, on August 21, 2000, NIEHS, RTP, NC. [PDF]

  • Confidence Interval Procedure Review

  • Draft Up-and-Down Procedure Background Review Document (April 14, 2000 - version reviewed by peer panel) [PDF]

Implementation Workshop

ICCVAM partnered with U.S. EPA and ILSI on the training workshop: Putting Acute Oral Toxicity Testing Guidelines into Practice, February 19-21, 2002, in Bethesda, MD. The ILSI Risk Science meeting brochure for this workshop are available on the ILSI Web Site.





  Back to Top NICEATM-ICCVAM:
Advancing Public Health and Animal Welfare