Updated 10/29/14, 12:55 a.m.

Just seconds after liftoff today, at 6:22 p.m. Eastern, an unmanned Orbital Sciences Antares rocket contracted by NASA failed and exploded feet above the launch pad. The incident happened at the space agency’s Wallops Island Flight Facility on the eastern shore of Virginia.

No one was injured, NASA has confirmed. Early reports estimate significant damage to equipment and facilities.

The rocket was set to bring 4,883 pounds of supplies and experiments to the International Space Station, a payload that included both public and private property: satellites, spacewalk gear, and student experiments.

“No cargo that was absolutely critical to us was lost on this flight. The [ISS] crew is in no danger,” said William Gerstenmaier, the NASA administrator in charge of human exploration.

Orbital Sciences Corporation will lead an investigation into the accident, with assistance from the Federal Aviation Administration.

A space enthusiast captured video of the explosion from the press viewing area, about five miles away from the launch pad:

A private pilot also took video of the incident “from 3,000 feet”:

And the best video we’ve found is a view of the launch even farther away than the press area, captured by a professional photographer. The Antares lifts off about a minute into the clip:

Post by Brian Garrett Photography.

Two previous Antares missions have successfully resupplied the station. The Antares system has only ever launched five times, including Tuesday’s attempt, and this mission carried the heaviest payload ever. NASA’s existing $1.9 billion contract with Orbital Sciences, the developer of Antares, entails eight total resupplying missions to the ISS.

An unmanned Russian resupply mission to the ISS, using a Soyuz craft, had already been scheduled to launch on Wednesday, October 28. The next unmanned U.S. resupply mission to the station—using a launch vehicle supplied by SpaceX, another American private contractor—is scheduled for December.

A NASA spokesman estimated that even if no more vehicles reached the station this year, the crew’s consumable supplies—that is, water, food, and oxygen—could last to March.

At a press conference after the accident, NASA and Orbital Science officials said they were very disappointed.

“We will come back and fly here at Wallops again,” said Frank Culbertson, Jr., the vice president for human spaceflight at Orbital Sciences and a former ISS commander. (Culbertson was the only American not on Earth on September 11, 2001.)

At sunrise, Culberton said, a team of investigators will begin tagging, locating, and investigating as much debris as they can recover at the crash site. He said video data and “reams of telemetry data” will also be analyzed. Log files and data were secured shortly after the accident to ensure full information is available for the investigation.