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Early Edition
New papers posted dailyOctober 29, 2014
- Giant cadherins Fat and Dachsous self-bend to organize properly spaced intercellular junctions
- Building carbon–carbon bonds using a biocatalytic methanol condensation cycle
- Nitric oxide negatively regulates AKT1-mediated potassium uptake through modulating vitamin B6 homeostasis in Arabidopsis
- Human NLRP3 inflammasome senses multiple types of bacterial RNAs
- Protease-based synthetic sensing and signal amplification
- Structural basis and distal effects of Gag substrate coevolution in drug resistance to HIV-1 protease
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Sulforaphane and autism spectrum disorder
A study finds that treatment with the broccoli-sprout extract sulforaphane improved performance on assessments for social responsiveness and verbal communication, among other indicators, of 29 men ages 13-27 with autism spectrum disorder, and that scores returned to pre-treatment levels following discontinuation of treatment.
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35,000 years of sea-level change
A 35,000-year reconstruction of global sea level and ice volume finds no evidence of sea-level oscillations greater than 20 cm between 6,000 years ago and around 150 years ago, when sea level began to rise.
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Disease transmission and antibiotic-induced hyperinflammation
Highly infectious individuals within a population, known as superspreaders, may be more tolerant to intestinal perturbations caused by antibiotic treatment than non-superspreaders, according to a study.
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